| Farcaster | – | – | 2022 | 1confirmation |
| Evidently AI, SAAS | – | – | 2022 | Framework Venture Partners |
| enspired Climate Tech, Austria | – | – | 2022 | 360 Capital |
| End Game | – | – | 2022 | 1confirmation |
| Encore | – | – | 2022 | Team8 |
| Embed Logistics | – | – | 2022 | Aleph |
| electrotempo.com EV Charging Network Intelligence | Pre-Seed | – | 2022 | Schematic Ventures |
| Eden Care RW | – | – | 2022 | Seedstars |
| Eclypsium | Growth | – | 2022 | Ten Eleven Ventures |
| Donde Enterprise Intelligence | – | – | 2022 | Next Frontier Capital |
| Doctomatic Aging, Spain | Seed | – | 2022 | Ship2B Ventures |
| Dentologie Healthcare | – | – | 2022 | Hyde Park Venture Partners |
| Dental Iberica | – | – | 2022 | Kibo Ventures |
| delphai Germany | – | – | 2022 | Newion |
| Deeto | – | – | 2022 | UpWest |
| Deep Sky | pre-Seed | – | 2022 | Brightspark Ventures |
| DeepNFTValue | – | – | 2022 | 1confirmation |
| Dcycle Climate, Spain | Seed | – | 2022 | Ship2B Ventures |
| Datasaur | – | – | 2022 | TenOneTen Ventures |
| Dana Aging, Spain | – | – | 2022 | Ship2B Ventures |
| Daily.dev Developer tools | – | – | 2022 | Aleph |
| Cysec Cybersecurity, Switzerland | – | – | 2022 | Karista |
| Custom Agronomics Sustainability / Advanced Manufacturing | – | – | 2022 | Inverness Graham |
| Credit Dharma FinTech, India | Seed | – | 2022 | 10x Founders |
| Creature Comforts | Stage Early | – | 2022 | Hanaco Ventures |
| Cotiss Supply Chain | – | – | 2022 | AfterWork Ventures |
| Corsha | Venture | – | 2022 | Ten Eleven Ventures |
| Constantinople Software | Seed | – | 2022 | AirTree Ventures |
| Concord Servicing Sustainability / Technology-Enabled Services / Software | – | – | 2022 | Inverness Graham |
| Commons Carbon credits & accounting, United States | series A | – | 2022 | Norrsken VC |